Steve Guise

Professional Experience

F. Hoffmann-La Roche AG

Global Head - Business Domains, Informatics

Jul 2022 - Present (Basel/Kaiseraugst, CH)

Responsible for Digital & Technology strategy for whole Roche Group.
Lead the Business Partnering & Delivery for Pharma, Diagnostics & Corporate.
Lead enterprise governance for CHF 2bn budget, directly responsible for CHF 1bn investment annually.
Manage the work of 5000+ internal and external talents.
Executive sponsor for key strategic partnerships (Veeva, IQVIA, Accenture, TCS).
Accountable for Quality, Compliance & Risk management (GDPR, GxP).
Drove modernisation and tech debt reduction through holistic SaaS/Cloud strategy.
Sponsor of S4/HANA implementation - biggest SAP project in the industry.
Co-developed Data & AI Strategy, delivering GenAI use-cases across the value chain.
Drove Product Management & SAFe methodology as part of agile transformation.
Responsible for M&A tech integrations (4-6 per year).
Champion & advocate for sustainability in business (Sustainability SteerCo member).

Global Head, Pharma Informatics (Pharma CIO)

Oct 2016 - Jun 2022 (Basel/Kaiseraugst, CH)

Technology partner to the Pharma Leadership Team & Pharma CEO.
Led Digital Strategy for Pharma - Accountable for executing implementation roadmap.
Digital Customer Engagement (EpiCX Program) - Veeva (US) & IQVIA (RoW).
R&D Cloud Platform implementation - Veeva R&D Cloud + other SaaS solutions.
Aligned MES platform program for Drug Product sites.
Provide leadership to 3000+ internal and external talents across 5 continents.
Responsible for CHF750mn investment annually.

Head - Software Center of Excellence, Diagnostics Information Solutions

Jun 2016 - Oct 2016 (Mountain View, CA)

Pioneer in Roche Digital Health and Insights business - founding member of new unit tasked with building the foundations of a 3rd pillar to Roche’s business.
Initial scale up of software development capability in the Bay Area.
Led the productisation and early launch of Roche’s Navify Tumor Board platform.

APAC Head, Pharma Informatics

Apr 2013 - May 2016 (Shanghai & Singapore)

Member of APAC Regional Leadership Team. Driver of Regional tech strategy.
Led the relocation of our Regional IT team from Shanghai to Kuala Lumpur.
Created and scaled up our shared service centre in San Jose, Costa Rica.
Led the creation of our Global Customer Experience team.

Global Head, Scientific Information Systems & Principal Architect

Mar 2010 - Apr 2013 (Basel, CH)

Led global team responsible for scientific system and platform development. Responsible for overall architecture of R&D system landscape & tec[...]

Site Head - Basel, Pharma Research Informatics

Oct 2008 - Mar 2010 (Basel, CH)

Led the Basel site Research Informatics team. Responsible for Bioinformatics, data science, software development, scientific workflows.

UCB Celltech Ltd.

Director, Informatics

Jan 2004 – Sep 2008 (Slough, UK)

Led team of Chem & Bioinformaticians supporting Research (~20 people).
Led the systems integration for Research following UCB’s acquisition of Celltech.
Responsible for all scientific systems in combined UCB Celltech.

AstraZeneca Ltd.

Senior Informatics Specialist

2001 – 2004 (Alderley Park, UK)

Cheminformatics specialist focused on structure activity relationship analysis and lead optimisation for Oncology research.
Key contributor to the integration of chemical information systems following the merger of Astra and Zeneca.
First line management role, leading a group of 3 Informatics Scientists.

Research Scientist, Discovery Chemistry department

Sep 1997 – 2001 (Alderley Park, UK)

Process development chemist - large scale laboratory.
Commissioned GxP compliant kilo lab to support Phase I clinical studies.

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Executive Profile